Which Defense Medical Logistics Standard Support (DMLSS) application is used by custodians to submit new item requests?

The correct choice for the application used by custodians to submit new item requests is the Item Request System. This platform is specifically designed for custodians to initiate new item requests, allowing them to manage inventory and ensure that the necessary medical supplies are available as needed.

The Item Request System streamlines the process for custodians by providing an efficient way to identify needs and submit requests directly within the Defense Medical Logistics Standard Support framework. This helps maintain the readiness and availability of medical items for healthcare providers within the military.

Other applications, such as the Vendors Portal, may deal with procurement processes or vendor management but are not specifically geared toward submitting new item requests by custodians. The CS and Order Management Application serve different functions in the logistics and supply chain processes, further clarifying why the Item Request System is the appropriate tool for this specific task.